Abstract: Existing control systems for plunger lift are characterized by single function with missing of systematic optimization capacities. In addition, these systems require inputting parameters depending only on theoretical models. Accordingly, innovative control systems for water drainage and gas production with plunger lift have been designed under multi-mode optimization. With STM32 single chip computer as the core, the newly-developed system is capable of capturing tubing pressure, casing pressure and travelling time of the plunger to wellhead in real time. Upon processing and optimization by the single chip computer, the system may effectively control pneumatic diaphragm valve. On-site application results show the innovative system can adjust production systems of gas producers in real time to achieve desirable fluid drainage performance and to enhance working efficiency significantly.