Abstract: A new technology of separate layer water flooding with eccentricity was put forward. The pipe constitution, work principle and the structure and technology target of main tools, such as eccentric water regulator with fix pressure and constant flow, self-sealing packer, were introduced. The testing technology is simple and the effective period is longer. The problems of pulling and running blanking plug as packer being sat etc. were avoided. The sealing of packer can be checked by itself. Field test shows that the pipe has reliability performance and convenience using.