Abstract: Well acidizing is one of the main styles to promote oil production and water injection. The present acidizing methods always show the problems of lower pressure and temperature endurances, less number of acidizing formation layers, difficulty of counter well washing. Through the researches of acidizing packer structure, cup sealing structure, cup material and multi-layer switcher, the technology fit for the requirement of high acidizing pressure in low and middle permeability formations and the requirement of multi-formations acidizing. It can be up to the highest pressure of 40 MPa with three acidizing formations. And it also can run counter well washing. This technology improves the development effects of low and middle permeability reservoirs in East Region of China.