Abstract: In order to overcome the difficulties in salt formation drilling, especially for Wuyang area, and to solve the problem exposed in slurry application of Well Y4 in Wuyang, a type of saturated salt resistant slurry system is developed, through the study of salt water drilling fluid formulation and the working principles of additives, and the analysis on the priority principles of the saline mud. The slurry makes Well Y4 drilling a success. It not only meets the needs of conventional salt formation drilling, but also is adaptive, environmental-friendly and economical.