Abstract: Regarding the problem of high temperature well corrosion serious influencing the normal production in oilfields, figuring out the reason to well corrosion, an YHZ series corrosion inhibitor was developed through orthogonal experiment. The formula is mainly the imidazoline derivatives and organic amine group, supplemented by high temperature resistant fluorocarbon imidazoline group. This agent shows good corrosion inhibition performance with average corrosion inhibition rate of 90 percent, which solve the problem of well corrosion in reservoirs with high temperature （higher than 100 degree）. Field application has achieved obvious effect and has shown a longer maintenance period of pumping wells.